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Resources and Publications

Human Evolutionary and Population Genomics

Resources and Publications

Resources and Publications

Human Evolutionary and Population Genomics

Lab Publications:

21. Homburger, J., Moreno-Estrada, A., Gignoux, C., Nelson, D., Sanchez, E., Ortiz-Tello, P., . . . Bustamante, C. (2015). Genomic Insights into the Ancestry and Demographic History of South America. PLoS Genet PLOS Genetics, 1-26. doi:10.1371/journal.pgen.1005602 [link]

Other Selected Publications:

2011 - 2014

20. Moreno-Estrada, A., Gignoux, C., Fernandez-Lopez, J., Zakharia, F., Sikora, M., & Contreras, A. et al. (2014). The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science, 344(6189), 1280-1285. http://dx.doi.org/10.1126/science.1251688 [link]

19. Sikora, M., Carpenter, M., Moreno-Estrada, A., Henn, B., Underhill, P., & Sánchez-Quinto, F. et al. (2014). Population Genomic Analysis of Ancient and Modern Genomes Yields New Insights into the Genetic Ancestry of the Tyrolean Iceman and the Genetic Structure of Europe. Plos Genetics, 10(5), e1004353. http://dx.doi.org/10.1371/journal.pgen.1004353 [link]

18. Moreno-Estrada, A., Gravel, S., Zakharia, F., McCauley, J., Byrnes, J., & Gignoux, C. et al. (2013). Reconstructing the Population Genetic History of the Caribbean. Plos Genetics, 9(11), e1003925. http://dx.doi.org/10.1371/journal.pgen.1003925 [link]

17. Gravel, S., Zakharia, F., Moreno-Estrada, A., Byrnes, J., Muzzio, M., & Rodriguez-Flores, J. et al. (2013). Reconstructing Native American Migrations from Whole-Genome and Whole-Exome Data. Plos Genetics, 9(12), e1004023. http://dx.doi.org/10.1371/journal.pgen.1004023 [link]

16. Moreno, A., & Sandoval, K. (2013). Diversidad genómica en México. Pasado indígena y mestizaje. Cuicuilco, 20(58), 249-276. [link]

15. Carpenter, M., Buenrostro, J., Valdiosera, C., Schroeder, H., Allentoft, M., & Sikora, M. et al. (2013). Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries. The American Journal Of Human Genetics, 93(5), 852-864. http://dx.doi.org/10.1016/j.ajhg.2013.10.002 [link]

14. Kenny, E., Timpson, N., Sikora, M., Yee, M., Moreno-Estrada, A., & Eng, C. et al. (2012). Melanesian Blond Hair Is Caused by an Amino Acid Change in TYRP1. Science, 336(6081), 554-554. http://dx.doi.org/10.1126/science.1217849 [link]

13. Sandoval, K., Moreno-Estrada, A., Mendizabal, I., Underhill, P., Lopez-Valenzuela, M., & Peñaloza-Espinosa, R. et al. (2012). Y-chromosome diversity in Native Mexicans reveals continental transition of genetic structure in the Americas. Am. J. Phys. Anthropol., 148(3), 395-405. http://dx.doi.org/10.1002/ajpa.22062 [link]

12. Antolin, M., Jenkins, K., Bergstrom, C., Crespi, B., De, S., & Hancock, A. et al. (2012). Evolution and Medicine in Undergraduate Education: A Prescription for All Biology Students. Evolution, 66(6), 1991-2006. http://dx.doi.org/10.1111/j.1558-5646.2011.01552.x [link]

11. Chen, R., Corona, E., Sikora, M., Dudley, J., Morgan, A., & Moreno-Estrada, A. et al. (2012). Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases. Plos Genetics, 8(4), e1002621. http://dx.doi.org/10.1371/journal.pgen.1002621 [link]

10. Henn, B., Botigué, L., Gravel, S., Wang, W., Brisbin, A., & Byrnes, J. et al. (2012). Genomic Ancestry of North Africans Supports Back-to-Africa Migrations. Plos Genetics, 8(1), e1002397. http://dx.doi.org/10.1371/journal.pgen.1002397 [link]

9. Keller, A., Graefen, A., Ball, M., Matzas, M., Boisguerin, V., & Maixner, F. et al. (2012). New insights into the Tyrolean Iceman\\\'s origin and phenotype as inferred by whole-genome sequencing. Nature Communications, 3, 698. http://dx.doi.org/10.1038/ncomms1701 [link]

2008 - 2010

8. Moreno-Estrada, A., Aparicio-Prat, E., Sikora, M., Engelken, J., Ramírez-Soriano, A., Calafell, F., & Bosch, E. (2010). African signatures of recent positive selection in human FOXI1. BMC Evol Biol, 10(1), 267. http://dx.doi.org/10.1186/1471-2148-10-267 [link]

7. Bryc, K., Velez, C., Karafet, T., Moreno-Estrada, A., Reynolds, A., & Auton, A. et al. (2010). Genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proceedings Of The National Academy Of Sciences, 107(Supplement_2), 8954-8961. http://dx.doi.org/10.1073/pnas.0914618107 [link]

6. Henn, B., Gravel, S., Moreno-Estrada, A., Acevedo-Acevedo, S., & Bustamante, C. (2010). Fine-scale population structure and the era of next-generation sequencing. Human Molecular Genetics, 19(R2), R221-R226. http://dx.doi.org/10.1093/hmg/ddq403 [link]

5. Acuna-Alonzo, V., Flores-Dorantes, T., Kruit, J., Villarreal-Molina, T., Arellano-Campos, O., & Hunemeier, T. et al. (2010). A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. Human Molecular Genetics, 19(14), 2877-2885. http://dx.doi.org/10.1093/hmg/ddq173 [link]

4. Moreno-Estrada, A., Tang, K., Sikora, M., Marques-Bonet, T., Casals, F., & Navarro, A. et al. (2009). Interrogating 11 Fast-Evolving Genes for Signatures of Recent Positive Selection in Worldwide Human Populations. Molecular Biology And Evolution, 26(10), 2285-2297. http://dx.doi.org/10.1093/molbev/msp134 [link]

3. Bosch, E., Laayouni, H., Morcillo-Suarez, C., Casals, F., Moreno-Estrada, A., & Ferrer-Admetlla, A. et al. (2009). Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD. BMC Genomics, 10(1), 338. http://dx.doi.org/10.1186/1471-2164-10-338 [link]

2. Moreno-Estrada, A., Casals, F., Ramirez-Soriano, A., Oliva, B., Calafell, F., Bertranpetit, J., & Bosch, E. (2008). Signatures of Selection in the Human Olfactory Receptor OR5I1 Gene. Molecular Biology And Evolution, 25(1), 144-154. http://dx.doi.org/10.1093/molbev/msm240 [link]

1. Morcillo-Suarez, C., Alegre, J., Sangros, R., Gazave, E., de Cid, R., & Milne, R. et al. (2008). SNP analysis to results (SNPator): a web-based environment oriented to statistical genomics analyses upon SNP data. Bioinformatics, 24(14), 1643-1644. http://dx.doi.org/10.1093/bioinformatics/btn241 [link]

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